Team

Nature Communications|The collaboration between He Hang's team and Deng Xingwang's team is the first to report on the advanced structure of plant chromatin at nucleosome resolution and analyze its molecular mechanism

Research direction: nucleosomes and chromatin

Corresponding author: Academician Deng Xingwang and Researcher He Hang

First authors: Dr. Sun Linhua, Zhou Jingru, Xu Xiao

Important contributions: Liu Yi, Ma Ni, Liu Yutong, Dr. Nie Wenchao, and Zou Ling

Official website link: http://www.pku-iaas.edu.cn/kyjz/1072.html

Original link:https://www.nature.com/articles/s41467-023-44347-z

Nature Plants|Xingwang Deng/Hang He analyzing the Mechanism of Light Signal Regulation at the Single Cell Level in Plants

Research Direction:Single cell, light signal

Corresponding author:Academician Deng Xingwang、Researcher He Hang

Lead author:Xue Han

Important contribution:Researcher Jian Li、Researcher Bosheng Li、Researcher Huawei Zhang and other multiple teachers and colleagues

Official website link: http://www.pku-iaas.edu.cn/kyjz/1007.html

Original link:https://www.nature.com/articles/s41477-023-01544-4

Kiwi Breeding 4.0 Begins! The team led by He Hang and Deng Xingwang successfully constructed two kiwi species T2T genomic maps

Research Direction:kiwifruit

Corresponding author: Researcher He Hang、Associate Researcher David Li、Academician Deng Xingwang、

Lead author:Xue Han、Lilin Zhang、Associate Researcher Qiong Zhang、

Important contribution:Ni Ma、Xiaoying Liu、Wenjing Tao、Zhiying Lou、Researcher Caihong Zhang

Official website link: http://www.pku-iaas.edu.cn/kyjz/622.html

Original link:https://doi.org/10.1016/j.molp.2022.12.022

Database link:http://182.92.183.62/

He Hang's research group, in collaboration with partners, reveals the contribution of indica rice introgression to the genetic improvement of japonica rice

Research Direction:Indica rice

Corresponding author:Researcher Longzhi Han、Researcher Hang He

Lead author:Di Cui、Han Zhou、Associate Researcher Xiaoding Ma

Important contribution:Professor Deng Xingwang、Researcher Maomao Li、Researcher Jianchang Sun、Researcher Guixiu Jin、Researcher Xianju Wang

Official website link: http://www.pku-iaas.edu.cn/kyjz/204.html

Original link:

Deng Xingwang's laboratory and He Hang's research group, together with collaborative labs, jointly decode the 'breeding selection fingerprints' in the modern maize breeding process

Research Direction:corn

Corresponding author:Professor Haiyang Wang、Associate Researcher Hang He

Lead author:Researche Baobao Wang、Zechuan Lin、Xin Li

Important contribution:

Official website link: http://www.pku-iaas.edu.cn/kyjz/156.html

Original link:https://www.nature.com/articles/s41588-020-0616-3

The first watermelon T2T reference genome and EMS saturated mutant library

Research Direction:watermelon

Corresponding author:Researcher Xingping Zhang、Researcher Hang He

Lead author:Researcher Yun Deng、Associate Researcher Shoucheng Liu、Yilin Zhang

Important contribution:Researcher Yudong Sun、Professor Deng Xingwang、Researcher Yunbi Xu

Official website link: http://www.pku-iaas.edu.cn/kyjz/449.html

Original link:https://doi.org/10.1016/j.molp.2022.06.010

Database link:http://www.watermelondb.cn

He Hang's team and collaborators from Peking University Institute of Modern Agriculture published a high-quality rye genome in Nature Genetics

Research Direction:rye

Corresponding author:Researcher Wang Daowen、Researcher Zhang Kunpu、 Professor Yang Qinghua、Researcher Yang Jianping

Lead author:Guangwei Li、Lijian Wang、Researcher Yang Jianping、Researcher He Hang、Huai bing Jin、Xuming Li、Associate Professor Ren Tianheng

Important contribution:Academician Deng Xingwang、Xue Han

Official website link: http://www.pku-iaas.edu.cn/kyjz/159.html

Original link:https://www.nature.com/articles/s41588-021-00808-z

Deng Xingwang/He Hang's team from Peking University reveals the genetic mechanism behind the formation of hybrid rice heterosis loci

Research Direction:rice

Corresponding author:Professor Deng Xingwang、Associate Researcher He Hang、Researcher Yang Yuanzhu

Lead author:Zechuan Lin

Important contribution:

Official website link:http://www.pku-iaas.edu.cn/kyjz/153.html

Original link:https://www.pnas.org/content/early /2020/02/13 /1919086117

Deng Xingwang/He Hang's Team from Peking University Reveals the Relationship between Light Signal Regulatory Networks and Plant Landing

Research Direction:optical signal

Corresponding author:Professor Deng Xingwang、Professor Zhong Bojian、Associate Researcher He Hang

Lead author:Xue Han

Important contribution:

Official website link:http://www.pku-iaas.edu.cn/kyjz/151.html

Original link:

Introduction of Researchers

Hang He Director of Agricultural Organization Big Data Platform

mailbox:hehang@pku.edu.cn

Research Direction: Bioinformatics, Plant Genomics, Plant Multiomics

Educational experience：

2009 - 2011 ,Postdoctoral fellow, Bioinformatics, Peking University
2004 - 2009 , Doctor of Science, Bioinformatics, Institute of Biophysics, Chinese Academy of Sciences
2000 - 2004 , Bachelor of Science, Applied Mathematics, Peking University

Work Experience：

2011 - 2020，Associate Researcher, Peking University
2020 - ，Researcher, Peking University

Database and Tools

The first T2T watermelon genome and the mutant library

Website: http://www.watermelondb.cn

Genomic Database for Actinidia Species

Website: http://182.92.183.62/

Single Cell Atlases of Arabidopsis De-Etiolating Seedlings

Website: http://182.92.183.62:4576/

Multiomics research

Bioinformatics is an emerging discipline in the field of life sciences that utilizes information technology to store, retrieve, and analyze large and complex biological data, thereby revealing the mysteries of biology. In recent years, with the continuous improvement of genome sequences and the development of various high-throughput data collection experimental methods, data mining and understanding have also played an increasingly important role in biological research. Our research group integrates different omics data through long-term genome, transcriptome, epigenetics, and phenotype research, uncovers the inherent correlations between different omics data, forms mathematical models of biological mechanisms, and discovers new regulatory laws through methods.

Research on Heterosis

Hybridity is a complex biological phenomenon commonly found in nature and has been widely applied in agricultural production. However, the molecular genetic mechanism of hybridization is still unclear. With the deepening and development of molecular biology, genomics, and bioinformatics research, utilizing systems biology methods to study the molecular mechanisms of hybrid dominance has important scientific significance and practical application value. The heterozygous offspring of parents with genotype heterogeneity have many different traits from their parents, which inevitably involves the interaction of parental genomes in the hybrid genetic background, leading to changes in gene expression regulation. At present, we use high-throughput sequencing technology to conduct whole genome analysis on different tissues and environmental conditions of a large number of hybrid combinations, exploring the regulatory mechanisms of genetic and epigenetic levels on plant heterosis performance, and comprehensively exploring the molecular mechanisms of heterosis.

Genomic selection

With the application of more new technologies in agricultural production, we can quickly explore functional genes in crops such as rice and maize from a large amount of genotype and phenotype data, while integrating multiple favorable traits to carry out whole genome selection breeding. At present, our research group has conducted high-throughput genotype and phenotype identification to analyze the germplasm resources and hybrid populations of various crops, establish the correlation between traits and markers at the whole genome level, further predict the trait performance of varieties through mathematical modeling, and carry out molecular design breeding.

Database and Tools

Through database tools, convenient data sharing is achieved, reducing data redundancy, ensuring data consistency, maintaining data independence, achieving centralized control of data, and greatly improving data maintainability.

Hang He Researcher

Researcher at Peking University, Director of Bioinformation Platform at Peking University Institute of Modern Agriculture, and Postdoctoral Fellow at Peking University

Jianxin Bian Associate Researcher

Associate Researcher of Bioinformation Platform and PhD holder at Northwest A&F University

Xue Han Associate Researche

Leader of kiwifruit precision design and breeding project, Postdoctoral Fellow of Peking University

Shoucheng Liu Associate Researche

Associate Researcher of Bioinformatics Platform, mainly responsible for bioinformatics analysis and cluster management

Kui Li Associate Researche

Associate Researcher of Bioinformatics Platform

Congcong Jin Research associate

Assistant Researcher of Crop Multiomics Laboratory

Shengzhang Zhu Visiting Scholar

Visiting Scholar of Crop Multiomics Laboratory

DiCui Visiting Scholar

Visiting Scholar of Crop Multiomics Laboratory

Xiuru Dai Visiting Schola

Visiting scholar on the bioinformatics platform, lecturer at Shandong Agricultural University, and doctoral candidate at Shandong Agricultural University

Zhiying Lou

Research Assistant for Bioinformatics Platform

Zizheng Ren

Research Assistant for Bioinformatics Platform

Shuai Ding

Research Assistant for Bioinformatics Platform

Guoliang Zhou

Research Assistant for Bioinformatics Platform

Xiaopeng Li

Research assistant for bioinformatics platform, responsible for bioinformatics analysis and cluster maintenance

Weimin Liu

Research Assistant for Bioinformatics Platform

Yutong Liu

Crop Multiomics Research Assistant

Hao Jiang

Research Assistant for Bioinformatics Platform

Xinlong Hu

Research Assistant for Bioinformatics Platform

Yan Wang

Research Assistant for Bioinformatics Platform

Yuan Lv

Research Assistant for Bioinformatics Platform

Zenhui Chen

Research Assistant for Bioinformatics Platform

Yuqi Guo

Research Assistant of Kiwi Research Group

Kai Wu

Research Assistant of Kiwi Research Group

Wudi Gai

Research Assistant of Kiwi Research Group

Che Liu

Research Assistant for Bioinformatics Platform

Xu Wang

Technician of Kiwi Research Group

Jingming Chen

Network administrator, network infrastructure maintenance, network security management, software maintenance, database maintenance, and comprehensive data center maintenance

Yilin Zhang

Visiting student in crop multi omics laboratory, doctoral student at Peking University

Ni Ma

Visiting student in crop multi omics laboratory, doctoral student at Peking University

Haiyue Zen

Visiting student in crop multi omics laboratory, doctoral student at Peking University

Yijun Chen

Visiting student in crop multi omics laboratory, doctoral student at Tel Aviv University in Israel

Qi Zhang

Visiting student in crop multi omics laboratory, doctoral student from Northwest A&F University

Kun Kang

Intern at the Kiwi Precision Design and Breeding Research Group, Master's student at Northwest A&F University

Yin Li

Intern at the Kiwi Precision Design and Breeding Research Group, Master's student at Northwest A&F University

Yuting He

Intern at the bioinformatics platform, master's student at South China Agricultural University

Educational experience：

Work Experience：

Hang He Researcher

Jianxin Bian Associate Researcher

Xue Han Associate Researche

Shoucheng Liu Associate Researche

Kui Li Associate Researche

Congcong Jin Research associate

Shengzhang Zhu Visiting Scholar

DiCui Visiting Scholar

Xiuru Dai Visiting Schola

Zhiying Lou

Zizheng Ren

Shuai Ding

Guoliang Zhou

Xiaopeng Li

Weimin Liu

Yutong Liu

Hao Jiang

Xinlong Hu

Yan Wang

Yuan Lv

Zenhui Chen

Yuqi Guo

Kai Wu

Wudi Gai

Che Liu

Xu Wang

Jingming Chen

Yilin Zhang

Ni Ma

Haiyue Zen

Yijun Chen

Qi Zhang

Kun Kang

Yin Li

Yuting He

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